Induction of heat-labile enterotoxin synthesis in enterotoxigenic Escherichia coli mitomycin C

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Induction of heat-labile enterotoxin synthesis in enterotoxigenic Escherichia coli mitomycin C.

Introduction of heat-labile toxin (LT) synthesis in enterotocigenic strains of Escherichia coli by mitomycin C (MTC) was demonstrated. Six enteropathogenic strains which produce LT were inducible, exhibiting an 896-fold increase in LT when compared to ininduced cultures. On the other hand, four nonenteropathogens and three other pathogens which produce only the heat-stable toxin were not induce...

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Escherichia coli Heat - labile Enterotoxin NUCLEOTIDE SEQUENCE

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ژورنال

عنوان ژورنال: Infection and Immunity

سال: 1975

ISSN: 0019-9567,1098-5522

DOI: 10.1128/iai.12.6.1271-1275.1975